Development of T cell immune responsiveness in the chicken.

  title={Development of T cell immune responsiveness in the chicken.},
  author={John W. White Patrick R. Lowenthal and T E Connick and P G McWaters and Jennifer J. York},
  journal={Immunology and cell biology},
  volume={72 2},
Chickens are highly susceptible to infection by opportunistic pathogens during the first few days after hatching. This observation has generally been attributed to an immaturity of the immune system; however, the mechanisms responsible are not known. This study investigated the ability of T cells from chickens of various ages to respond to immune stimulation. Splenic T cells were cultured in vitro and stimulated with various mitogens including Con A, PHA and monoclonal anti-CD3 antibody. T… CONTINUE READING

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