Development of Self-assembled Amphiphilic Oligo-urethanes as Cardiovascular Drug Delivery Platforms

@inproceedings{Rajora2015DevelopmentOS,
  title={Development of Self-assembled Amphiphilic Oligo-urethanes as Cardiovascular Drug Delivery Platforms},
  author={M. P. Rajora},
  year={2015}
}
Current drug-coated balloon (DCB) technologies, used to prevent percutaneous coronary intervention-related restenosis via antiproliferative agent delivery to arterial lesions, are associated with systemic drug loss during catheter tracking and inefficient drug delivery to target tissues. This thesis aimed to study and synthesize novel amphilphilic oligo-urethanes (AOUs) as DCB drug carriers comprised of polyol, lysine diisocyanate and perfluoroalcohol (PFA) segments to enhance drug release… CONTINUE READING

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