Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant.

@article{Garon2003DevelopmentOR,
  title={Development of RTS,S/AS02: a purified subunit-based malaria vaccine candidate formulated with a novel adjuvant.},
  author={Nathalie Garçon and D. Gray Heppner and Joe Cohen},
  journal={Expert review of vaccines},
  year={2003},
  volume={2 2},
  pages={
          231-8
        }
}
  • Nathalie Garçon, D. Gray Heppner, Joe Cohen
  • Published in Expert review of vaccines 2003
  • Biology, Medicine
  • During the past decade, tremendous progress has been made in process development allowing for the production of large quantities of recombinant antigens, as well as in the understanding of the immune mechanisms underlying protection. Parallel to this, various and numerous adjuvant systems have been developed and tested in animal models and in clinical trials but have rarely induced protection. This review will discuss the development of a new adjuvant system (AS02) in combination with a malaria… CONTINUE READING

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