Development of Multidrug Resistance during Standardized Treatment in a Patient with Drug-Sensitive Tuberculosis

@inproceedings{Jeong2012DevelopmentOM,
  title={Development of Multidrug Resistance during Standardized Treatment in a Patient with Drug-Sensitive Tuberculosis},
  author={Yun-Jeong Jeong and Hyo Jae Kang and Sun Mi Choi and Sung Koo Han and Jae Joon Yim},
  year={2012}
}
Standard short-course chemotherapy (SSC) is recommended for new patients with pulmonary tuberculosis (TB). This approach has been regarded as among the most effective tools for preventing the development of resistance to anti-TB drugs. We report on the development of multidrug-resistance during SSC in a patient with drug-susceptible TB. Isoniazid, rifampin, pyrazinamide, and ethambutol were started, and negative culture conversion was obtained. Ethambutol was discontinued after 5 weeks of… CONTINUE READING

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