Development of MRI/NIRF 'activatable' multimodal imaging probe based on iron oxide nanoparticles.

Abstract

A fabrication method of Cy5.5-MMP substrate and PEG conjugated iron oxide nanoparticles with thin silica coating (PCM-CS) and its potential as an 'activatable' dual imaging probe for tumor imaging is described in this report. PCM-CS showed an intensity-averaged diameter of 43.1 ± 6.3 nm by dynamic light scattering without any noticeable aggregation over 7… (More)
DOI: 10.1016/j.jconrel.2011.07.019

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