Development of Highly Affine and Selective Fluorinated Cannabinoid Type 2 Receptor Ligands.

@article{Moldovan2017DevelopmentOH,
  title={Development of Highly Affine and Selective Fluorinated Cannabinoid Type 2 Receptor Ligands.},
  author={Rareş-Petru Moldovan and Kristin Hausmann and Winnie Deuther-Conrad and Peter Brust},
  journal={ACS medicinal chemistry letters},
  year={2017},
  volume={8 5},
  pages={566-571}
}
Cannabinoid type 2 receptors (CB2 receptors) are involved in various pathological processes, and the visualization of their in vivo availability with positron emission tomography (PET) is of high interest. The study focuses on the introduction of fluorine into the structure of the highly affine and selective CB2 receptor ligand N-(adamantan-1-yl)-5-ethyl-2… CONTINUE READING