Development of HPLC method for the determination of levosulpiride in human plasma.

@article{Jin2004DevelopmentOH,
  title={Development of HPLC method for the determination of levosulpiride in human plasma.},
  author={Su-Eon Jin and Eunmi Ban and Yang-Bae Kim and C. Kim},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2004},
  volume={35 4},
  pages={
          929-36
        }
}
  • Su-Eon Jin, Eunmi Ban, +1 author C. Kim
  • Published in
    Journal of pharmaceutical and…
    2004
  • Chemistry, Medicine
  • A rapid and simple high performance liquid chromatography (HPLC) method was developed and validated for determination of levosulpiride in human plasma. After extraction with ethylacetate/methylene chloride (5:1, v/v), analysis of levosulpiride in plasma samples was carried out using a reverse phase C18 column with fluorescence detector (maximum excitation at 300 nm and maximum emission at 365 nm) for separation and quantification. A mixture of methanol-20 mM phosphate buffer (pH 3.5, 16:84, v/v… CONTINUE READING

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