Development of HPLC-Orbitrap method for identification of N-bearing molecules in complex organic material relevant to planetary environments

  title={Development of HPLC-Orbitrap method for identification of N-bearing molecules in complex organic material relevant to planetary environments},
  author={Thomas Gautier and Isabelle Schmitz-Afonso and David Touboul and Cyril Szopa and Arnaud Buch and Nathalie Carrasco},
Although the Cassini Spacecraft and the Huygens lander provided numerous information about Titan atmospheric chemistry and the formation of its aerosols, the exact composition of these aerosols still remains unknown. A fruitful proxy to investigate these aerosols is the use of laboratory experiments that allow producing and studying analogs of Titan aerosol, the so-called tholins. Even when produced in the laboratory, unveiling the exact composition of the aerosol remains problematic due to the… Expand

Figures and Tables from this paper

Development of liquid chromatography high resolution mass spectrometry strategies for the screening of complex organic matter: Application to astrophysical simulated materials.
This work points out the suitability of these two novel LC-HRMS strategies for untargeted analysis of complex environmental samples. Expand
Data-Driven UPLC-Orbitrap MS Analysis in Astrochemistry
By means of this time-resolving high resolution mass spectrometric method, this work goes one step further toward the characterization of chemical structures within complex extraterrestrial mixtures, enabling a better understanding of organic chemical evolution, from interstellar ices toward small bodies in the Solar System. Expand
Structural elucidation of soluble organic matter: Application to Titan's haze
Abstract The origin and evolution of organic matter in the solar system intertwines astrobiology and planetary geochemistry issues. To observe the contribution of atmospheric processes in theExpand
Identification of organic molecules with a laboratory prototype based on the Laser Ablation-CosmOrbitrap
In the Solar System, extra-terrestrial organic molecules have been found on cometary primitive objects, on Titan and Enceladus icy moons and on Mars. Identification could be achieved for simpleExpand
Structural elucidation of soluble organic 1 matter : application to Titan ’ s haze 2 3
16 The origin and evolution of organic matter in the solar system intertwines astrobiology and 17 planetary geochemistry issues. To observe the contribution of atmospheric processes in the 18Expand
Comparison of soluble and insoluble organic matter in analogues of Titan's aerosols
Abstract Titan, the biggest moon of Saturn, has a thick atmosphere which presents similarities with the one thought to be on Earth at its beginning. The study of Titan's photochemical haze is thus aExpand
Suggested plausible structures for Titan's haze analogs using tandem mass spectrometry
Abstract Understanding the formation and composition of the organic photochemical haze produced in Titan's upper atmosphere is an important milestone in prebiotic chemistry, for the early EarthExpand
Structural Study of Analogues of Titan’s Haze by Trapped Ion Mobility Coupled with a Fourier Transform Ion Cyclotron Mass Spectrometer
Analyzing the mobility peak width versus m/z shows a linear increase in isomeric diversity between m/Z 170 and 350 and a near plateau in diversity at higher m/ z for the N-PAH-like structure, and peak parameters other than the CCS value are explored. Expand
High resolution mass spectrometry for future space missions: comparative analysis of complex organic matter with LAb-CosmOrbitrap and LDI-FTICR.
The relevance of a space laser-CosmOrbitrap instrument for the future planetary exploration is demonstrated and the detection of HCN confirms previous results obtained with laboratory Electrospray Ionization studies about the understanding of polymeric patterns for the formation of tholins. Expand
Chemical composition of Pluto aerosol analogues
Abstract Photochemical aerosols were observed in Pluto atmosphere during the New Horizons flyby on July 14th, 2015, as several thin haze layers extending at >350 km of altitude. This flyby has raisedExpand


Characterization of laboratory analogs of interstellar/cometary organic residues using very high resolution mass spectrometry
Studying the chemical composition of organic matter in astrophysical environments is an important means to improve our understanding of its origin and evolution. This organic matter evolves fromExpand
Organic environments on Saturn’s moon, Titan: Simulating chemical reactions and analyzing products by FT-ICR and ion-trap mass spectrometry
The present work demonstrates that ESI-MS coupled with FT-ICR is a suitable and “intact” method to analyze tholin components formed under anaerobic conditions; only species with CxHyNz are detected for freshly prepared and harvested samples. Expand
Identification of nitrogenous organic species in Titan aerosols analogs: Nitrogen fixation routes in early atmospheres
Abstract Titan, an icy world surrounded by auburn organic haze, is considered as one of the best targets for studying abiotic planetary organic chemistry. In spite of a great many efforts being made,Expand
Tholinomics--chemical analysis of nitrogen-rich polymers.
The polymeric composition of Titan's tholins--laboratory analogues of Titan’s aerosols--is elucidated using high-resolution mass spectrometry, and the smallest species of a subset of families are identified as linear and cyclic amino nitrile compounds of great astrobiological interest. Expand
Nitrogen incorporation in Titan's tholins inferred by high resolution orbitrap mass spectrometry and gas chromatography–mass spectrometry
Abstract Influx of solar photons and heavy charged particles from Saturn's magnetosphere on Titan's atmosphere – mainly comprised of methane and nitrogen – induce an intense organic photochemistryExpand
The mechanism of hexamethylenetetramine (HMT) formation in the solid state at low temperature.
The fruitful interplay between theory and experiment has allowed establishing that the mechanism in the solid state at low temperature is different from the one proposed in liquid phase, in which a new intermediate has been identified. Expand
Identification of nitrogenous organic species in Titan aerosols analogs: Implication for prebiotic chemistry on Titan and early Earth
Abstract Titan has a significant atmosphere composed primarily of nitrogen and methane with a significant organic haze component. Its nitrogen-rich atmosphere, abundant organics, and liquid surfaceExpand
Identification of primary amines in Titan tholins using microchip nonaqueous capillary electrophoresis
Abstract Titan, the moon of Saturn with a thick atmosphere and an active hydrocarbon-based weather cycle, is considered the best target in the solar system for the study of organic chemistry on aExpand
New insights into the structure and chemistry of Titan's tholins via13C and 15N solid state nuclear magnetic resonance spectroscopy
Tholins are complex C,N-containing organic compounds produced in the laboratory. They are considered to provide materials that are analogous to those responsible for the haze observed in Titan'sExpand
Analysis of Titan tholin pyrolysis products by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
The reddish brown haze that surrounds Titan, Saturn's largest moon, is thought to consist of tholin-like organic aerosols. Tholins are complex materials of largely unknown structure. The very highExpand