Development of Electrochemiluminescent Serology Assays to Measure the Humoral Response to Antigens of Respiratory Syncytial Virus

@inproceedings{Maifeld2016DevelopmentOE,
  title={Development of Electrochemiluminescent Serology Assays to Measure the Humoral Response to Antigens of Respiratory Syncytial Virus},
  author={Sarah V. Maifeld and Bodrey W Ro and Hoyin Mok and Marla Chu and Li Yu and Ryan Yamagata and Tansy Leonardson and Vera Chio and Bandita Parhy and Samuel Byeongjun Park and Marcia Carlson and Shushil Machhi and Nancy D Ulbrandt and Ann R Falsey and Edward E. Walsh and Conan K. Wang and Mark T. Esser and Fengrong Zuo},
  booktitle={PloS one},
  year={2016}
}
Sensitive and precise serology assays are needed to measure the humoral response to antigens of respiratory syncytial virus (RSV) following natural infection or vaccination. We developed and evaluated a collection of electrochemiluminescent (ECL) serology assays using four RSV antigens (F, N, Ga and Gb). To assess the merits of ECL technology, the four ECL serology assays were evaluated using a well-characterized "gold standard" panel of acute and convalescent serum samples from fifty-nine RSV… CONTINUE READING