Development of Dermal Films Containing Miconazole Nitrate

@article{Brsan2018DevelopmentOD,
  title={Development of Dermal Films Containing Miconazole Nitrate},
  author={Magdalena B{\^i}rsan and Mihai Apostu and Nicoleta Todoran and Paula Antonoaea and Aura Rusu and Adriana Ciurba},
  journal={Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry},
  year={2018},
  volume={23}
}
  • M. Bîrsan, M. Apostu, A. Ciurba
  • Published 1 July 2018
  • Chemistry
  • Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
This study aims to develop new antifungal dermal films based on their mechanical properties (elongation, adhesion, behaviour towards vapour moisture) and the in vitro availability of miconazole nitrate, used as a pharmaceutical active ingredient in various concentrations. The three polymeric films prepared were translucent or shiny, with the surface of 63.585 cm2, 0.20–0.30 mm thickness, and content of miconazole nitrate of 3.931 or 15.726 mg·cm2. The mechanical resistance and elongation tests… 

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