Development of Cucumber mosaic virus as a vector modifiable for different host species to produce therapeutic proteins

@article{Matsuo2006DevelopmentOC,
  title={Development of Cucumber mosaic virus as a vector modifiable for different host species to produce therapeutic proteins},
  author={Kouki Matsuo and Jin- Sung Hong and Noriko Tabayashi and Akira Ito and Chikara Masuta and Takeshi Matsumura},
  journal={Planta},
  year={2006},
  volume={225},
  pages={277-286}
}
We have developed Cucumber mosaic virus (CMV) as a plant virus vector especially for production of pharmaceutical proteins. The CMV vector is a vector modifiable for different host plants and does not require further engineering steps. CMV contains three genomic RNA molecules (RNAs 1–3) necessary for infectivity. With this system, instead of creating different vector constructs for each plant we use, we take advantage of the formation of pseudrecombinants between two CMV isolates by simply… CONTINUE READING

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Advances in virus research • 2003
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