Development of Adjuvanted Solid Fat Nanoemulsions for Pulmonary Hepatitis B Vaccination.

Abstract

Pulmonary vaccination is one of the most promising routes for immunization owing to its noninvasive nature and induction of strong mucosal immunity and systemic response. In the present study, recombinant hepatitis B surface antigen loaded solid fat nanoemulsions (SFNs) as carrier system and monophosphoryl lipid A as an adjuvant-carrier system was prepared… (More)
DOI: 10.1016/j.xphs.2018.02.007

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