Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions.

@article{Slotkin1987DevelopmentO,
  title={Development of [3H]nicotine binding sites in brain regions of rats exposed to nicotine prenatally via maternal injections or infusions.},
  author={Theodore A. Slotkin and Lisa A. Orband-Miller and Kaila Queen},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1987},
  volume={242 1},
  pages={232-7}
}
The fetal and postnatal development of binding sites for [3H]nicotine was examined in brain regions of normal rats and rats whose mothers received nicotine injections or infusions, starting before fetal implantation (gestational day 4) and continuing to gestational day 20. The normal ontogenetic pattern of binding indicated a small but detectable… CONTINUE READING