Development of [11C]/[3H]THK-5351 - A potential novel carbon-11 tau imaging PET radioligand.

Abstract

INTRODUCTION Due to the rise in the number of patients with dementia the imperative for finding new diagnostic and treatment options becomes ever more pressing. While significant progress has been made in PET imaging of Aβ aggregates both in vitro and in vivo, options for imaging tau protein aggregates selectively are still limited. Based on the work… (More)
DOI: 10.1016/j.nucmedbio.2016.12.004

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