Development block of golden hamster ICSI embryos is associated with decreased expression of HDAC1, HSPA1A and MYC.


We have investigated the mechanism for embryo development block in vitro and to improve the development rate of golden hamster embryos in vitro. Intracytoplasmic sperm injection (ICSI) technique was used to produce golden hamster ICSI embryos. The changes in the histone acetylation and the expression of histone deacetylase and related genes were analyzed by… (More)
DOI: 10.1002/cbin.10319