Development and validation of the medication-based disease burden index.

  title={Development and validation of the medication-based disease burden index.},
  author={Johnson George and Tam D Vuong and Michael J. Bailey and David C. M. Kong and Jennifer L. Marriott and Kay Stewart},
  journal={The Annals of pharmacotherapy},
  volume={40 4},
BACKGROUND Medication lists offer an alternative source of data on comorbidities and disease burden. OBJECTIVE To develop and validate the Medication-Based Disease Burden Index (MDBI). METHODS A list of medications corresponding to the leading causes of global death was pilot tested and finalized by an expert panel. The resulting index was tested on drug regimens of patients at risk of medication misadventure. Criterion validity of the index was established against Charlson's index and… CONTINUE READING

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