Development and validation of an OECD reproductive toxicity test guideline with the pond snail Lymnaea stagnalis (Mollusca, Gastropoda).

@article{Ducrot2014DevelopmentAV,
  title={Development and validation of an OECD reproductive toxicity test guideline with the pond snail Lymnaea stagnalis (Mollusca, Gastropoda).},
  author={Virginie Ducrot and Clare E Askem and Didier Azam and Denise Brettschneider and Rebecca Brown and Sandrine Charles and Ma{\"i}ra Coke and Marc Collinet and Marie-Laure Delignette-Muller and Carole Forfait-Dubuc and Henrik Holbech and Thomas H. Hutchinson and Arne Jach and Karin Lund Kinnberg and C{\'e}dric Lacoste and Gareth Le Page and Peter Matthiessen and Joerg Oehlmann and Lynsey Rice and Edward Roberts and Katharina Ruppert and Jessica Elphinstone Davis and Clemence Veauvy and Lennart Weltje and Ruth Wortham and Laurent Lagadic},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={2014},
  volume={70 3},
  pages={605-14}
}
The OECD test guideline development program has been extended in 2011 to establish a partial life-cycle protocol for assessing the reproductive toxicity of chemicals to several mollusk species, including the great pond snail Lymnaea stagnalis. In this paper, we summarize the standard draft protocol for a reproduction test with this species, and present inter-comparison results obtained in a 56-day prevalidation ring-test using this protocol. Seven European laboratories performed semi-static… CONTINUE READING
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