Development and validation of a sensitive, high-throughput bioassay for the adhesion of radiolabeled E. coli to uroepithelial cells in vitro.

@article{Mathison2013DevelopmentAV,
  title={Development and validation of a sensitive, high-throughput bioassay for the adhesion of radiolabeled E. coli to uroepithelial cells in vitro.},
  author={Bridget D. Mathison and Lindsey Kimble and Kerrie L. Kaspar and Christina Khoo and Boon P. Chew},
  journal={Journal of natural products},
  year={2013},
  volume={76 9},
  pages={1605-11}
}
Vaccinium macrocarpon (cranberry) products have been used to prevent uropathogenic Escherichia (E.) coli adherence to uroepithelial cells (UEC) and may help reduce risk of urinary tract infection. Reported herein are the development and validation of an assay to assess antiadhesion activity of V. macrocarpon extracts and human urine. P-fimbriated E. coli… CONTINUE READING