Development and validation of a flow-injection assay for dissolution studies of the anti-depressant drug venlafaxine.

Abstract

The first flow-injection method has been developed, optimized and validated for the determination of venlafaxine, an antidepressant drug. The method is based on a direct measurement of the absorbance of the analyte in an acidic medium, at 274 nm. Flow-injection parameters, such as sample injection volume and flow rate, were studied and optimized. The… (More)

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@article{Tzanavaras2005DevelopmentAV, title={Development and validation of a flow-injection assay for dissolution studies of the anti-depressant drug venlafaxine.}, author={Paraskevas D. Tzanavaras and Aspasia Verdoukas and Demetrius G. Themelis}, journal={Analytical sciences : the international journal of the Japan Society for Analytical Chemistry}, year={2005}, volume={21 12}, pages={1515-8} }