Development and validation of InnoQuant™, a sensitive human DNA quantitation and degradation assessment method for forensic samples using high copy number mobile elements Alu and SVA.

@article{Pineda2014DevelopmentAV,
  title={Development and validation of InnoQuant™, a sensitive human DNA quantitation and degradation assessment method for forensic samples using high copy number mobile elements Alu and SVA.},
  author={Gina M Pineda and Anne H Montgomery and Robyn E Thompson and Brooke Indest and Marion Carroll and Sudhir K. Sinha},
  journal={Forensic science international. Genetics},
  year={2014},
  volume={13},
  pages={224-35}
}
There is a constant need in forensic casework laboratories for an improved way to increase the first-pass success rate of forensic samples. The recent advances in mini STR analysis, SNP, and Alu marker systems have now made it possible to analyze highly compromised samples, yet few tools are available that can simultaneously provide an assessment of quantity, inhibition, and degradation in a sample prior to genotyping. Currently there are several different approaches used for fluorescence-based… CONTINUE READING
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