Development and testing of gold nanoparticles for drug delivery and treatment of heart failure: a theranostic potential for PPP cardiology

  title={Development and testing of gold nanoparticles for drug delivery and treatment of heart failure: a theranostic potential for PPP cardiology},
  author={Mykola Ya. Spivak and Rostyslav V Bubnov and Ilya M Yemets and Liudmyla M. Lazarenko and Natalia O. Tymoshok and Zoia R Ulberg},
  booktitle={EPMA Journal},
Nanoscale gold particles (AuNPs) have wide perspectives for biomedical applications because of their unique biological properties, as antioxidative activity and potentials for drug delivery. The aim was to test effects of AuNPs using suggested heart failure rat model to compare with proved medication Simdax, to test gold nanoparticle for drug delivery, and to test sonoporation effect to increase nanoparticles delivery into myocardial cells. We performed biosafety and biocompatibility tests for… CONTINUE READING
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