Development and optimization of high-throughput methods to measure Plasmodium falciparum-specific growth inhibitory antibodies.

@article{Persson2006DevelopmentAO,
  title={Development and optimization of high-throughput methods to measure Plasmodium falciparum-specific growth inhibitory antibodies.},
  author={Kristina E. M. Persson and Chee Teik Lee and Kevin Marsh and James G Beeson},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 5},
  pages={1665-73}
}
Antibodies that inhibit replication of Plasmodium falciparum in erythrocytes are thought to be important both in acquired immunity to malaria and as mediators of immunity generated by candidate blood-stage vaccines. However, several constraints have limited the study of these functional antibodies in population studies and vaccine trials. We report the development and optimization of high-throughput growth inhibition assays with improved sensitivity that use minimal volumes of test serum. The… CONTINUE READING
58 Citations
27 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 27 references

Similar Papers

Loading similar papers…