Development and neurophysiology of mentalizing.

@article{Frith2003DevelopmentAN,
  title={Development and neurophysiology of mentalizing.},
  author={Uta Frith and Chris D. Frith},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  year={2003},
  volume={358 1431},
  pages={
          459-73
        }
}
  • U. Frith, C. Frith
  • Published 29 March 2003
  • Psychology, Biology
  • Philosophical transactions of the Royal Society of London. Series B, Biological sciences
The mentalizing (theory of mind) system of the brain is probably in operation from ca. 18 months of age, allowing implicit attribution of intentions and other mental states. Between the ages of 4 and 6 years explicit mentalizing becomes possible, and from this age children are able to explain the misleading reasons that have given rise to a false belief. Neuroimaging studies of mentalizing have so far only been carried out in adults. They reveal a system with three components consistently… 

Figures from this paper

Effects of aging on mindreading ability through the eyes: An fMRI study

Changes of brain activity in the neural substrates for theory of mind during childhood and adolescence

It is considered that the age‐related brain activity observed in the present study may be associated with the maturation of the prefrontal cortex and the associated development of cognitive functions.

Towards a neurocognitive theory of mind: how control and reasoning processes contribute to adult mentalizing

A neurocognitive account of ToM should describe a flexible system which adapts to the specific conceptual and contextual demands of the social world at that time, as well as identifying two accounts of control processes for ToM in vlPFC and dmPFC.

Functional activity and effective connectivity of the posterior medial prefrontal cortex during processing of incongruent mental states

The findings suggest that the bilateral temporal cortex engages in the construction and adjustment of diverging mental states by encoding relevant environmental information and the pMPFC inhibits this stimulus‐bound processing which helps to compute discrepant mental states and process another's false belief decoupled from one's own perception of reality.

Dalila Morais Teixeira

Theory of Mind (ToM), a crucial process of social cognition, refers to making predictions about people’s actions based on their mental states, representing the basis of human social communication and

Theory of mind performance in children correlates with functional specialization of a brain region for thinking about thoughts.

Between ages 5 and 11 years, responses in the bilateral TPJ became increasingly specific to stories describing mental states as opposed to people's appearance and social relationships, and how behavioral and neural changes can be related in development is provided.

The ventromedial prefrontal cortex is involved in understanding affective but not cognitive theory of mind stories

In the VM group, performance in the affective ToM was significantly impaired as compared to cognitive ToM stories, and ratings of levels of emotionality of each story suggested that levels of affective load correlated with number of errors in the stories, indicating that the more the emotional load involved in the story the greater the difficulty posed for the subjects in this group.

Influence of goals on observation of actions : functional neuroimaging studies

Three experiments using event-related functional magnetic resonance imaging in healthy volunteers were performed to clarify the involvement of brain regions in important components of the ToM capacity and the role of goals in the neural basis of mentalising is discussed.

Extensive Left Temporal Pole Damage Does Not Impact on Theory of Mind Abilities

The finding suggests that, despite its consistently observed activation in neuroimaging studies involving ToM tasks, the left TP is not necessary for ToM reasoning, at least in nonverbal conditions and as long as its right counterpart is preserved.
...

References

SHOWING 1-10 OF 154 REFERENCES

Interacting minds--a biological basis.

Observations suggest that the ability to mentalize has evolved from a system for representing actions, and medial prefrontal regions are concerned with explicit representation of states of the self.

Modeling other minds

Nine normal volunteers performed a ‘theory of mind’ task while their regional brain blood flow pattern was recorded using the PET [15O]H2O technique, suggesting that when inferential reasoning depends on constructing a mental model about the beliefs and intentions of others, the participation of the prefrontal cortex is required.

Other minds in the brain: a functional imaging study of “theory of mind” in story comprehension

A PET Investigation of the Attribution of Intentions with a Nonverbal Task

The data suggest that attribution of intentions to others is associated with a complex cerebral activity involving the right medial prefrontal cortex when a nonverbal task is used.

"Theory of mind" impairments and their relationship to executive functioning following frontal lobe excisions.

The theory of mind was investigated in patients with unilateral frontal lobe lesions and the ability to infer first- and second-order beliefs was tested by requiring subjects to listen to stories in which a protagonist acted upon a false belief.

Dissociation between 'theory of mind' and executive functions in a patient with early left amygdala damage.

It is concluded that theory of mind is not simply a function of more general executive functions, and that executive functions can develop and function on-line, independently of theory ofMind.

Cognitive and emotional influences in anterior cingulate cortex

Movement and Mind: A Functional Imaging Study of Perception and Interpretation of Complex Intentional Movement Patterns

A functional neuroimaging study with positron emission tomography in which six healthy adult volunteers were scanned while watching silent computer-presented animations showed increased activation in association with mental state attribution in four main regions: medial prefrontal cortex, temporoparietal junction, basal temporal regions, and extrastriate cortex.

What Does the Frontomedian Cortex Contribute to Language Processing: Coherence or Theory of Mind?

The results clearly show that the FMC plays a role in coherence processes even in the absence of concomitant ToM processes, and support the view of this cortex having a domain-independent functionality related to volitional aspects of the initiation and maintenance of nonautomatic cognitive processes.

Mind Reading: Neural Mechanisms of Theory of Mind and Self-Perspective

Divergent neural activations in response to TOM and SELF suggest that these important differential mental capacities of human self-consciousness are implemented at least in part in distinct brain regions.
...