Development and in vitro evaluation of expandable gastroretentive dosage forms based on compressed collagen sponges.

Abstract

The objective of this study was to develop and evaluate new collagen gastroretentive dosage forms (GRDFs) which expand in the stomach after contact with gastric fluids. The GRDFs should remain in the stomach for a prolonged period of time due to their size. The dosage forms were prepared from collagen sponges. The sponges were manufactured by freeze-drying… (More)

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Cite this paper

@article{Groening2006DevelopmentAI, title={Development and in vitro evaluation of expandable gastroretentive dosage forms based on compressed collagen sponges.}, author={Ruediger Groening and Christina Cloer and Rotraut Stephanie M{\"{u}ller}, journal={Die Pharmazie}, year={2006}, volume={61 7}, pages={608-12} }