Development and function of bombesin-like peptides and their receptors.

  title={Development and function of bombesin-like peptides and their receptors.},
  author={Hiroko Ohki-Hamazaki and Maiko Iwabuchi and Fumihiko Maekawa},
  journal={The International journal of developmental biology},
  volume={49 2-3},
Amphibian bombesin and its related peptides consist a family of neuropeptides in many vertebrate species. Bombesin and two major bombesin-like peptide in mammals, gastrin-releasing peptide (GRP) and neuromedin B (NMB), have been shown to elicit various physiological effects. These include inhibition of feeding, smooth muscle contraction, exocrine and endocrine secretions, thermoregulation, blood pressure and sucrose regulations and cell growth. Receptors for GRP and NMB (GRP-R and NMB-R), as… CONTINUE READING
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