Development and evaluation of transdermal gel of acyclovir using Nerolidol as penetration enhancer

  title={Development and evaluation of transdermal gel of acyclovir using Nerolidol as penetration enhancer},
  author={Pa Ps and Chavanke Da and Nevelichuk Vv and Bandivadekar Pv and Patil Bu and Mahajan Sr and Vaditake Kt},
  journal={Journal of Pharmacognosy and Phytochemistry},
  • Pa Ps, C. Da, +4 authors Vaditake Kt
  • Published 1 September 2018
  • Chemistry
  • Journal of Pharmacognosy and Phytochemistry
The aim of this study was to investigate the effect of Nerolidol on the penetration of Acyclovir in the form of transdermal gel formulation. Different formulations were prepared containing different concentrations of Nerolidol (0-5%) using Aloe vera gel as a base. Formulations evaluated for pH, Viscosity, Percent drug content, Spreadability, Diffusion study and In-vitro permeation study. Rheological study showed that viscosity is inversely proportional to the rate of shear and thus the system… Expand

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