Development and evaluation of the tablets coated with the novel formulation termed thin-layer sugarless coated tablets.

@article{Ohmori2004DevelopmentAE,
  title={Development and evaluation of the tablets coated with the novel formulation termed thin-layer sugarless coated tablets.},
  author={Shinji Ohmori and Yasuo Ohno and Tadashi Makino and Toshio Kashihara},
  journal={International journal of pharmaceutics},
  year={2004},
  volume={278 2},
  pages={
          459-69
        }
}
The purpose of this study was to develop and evaluate the thin-layer sugarless coated tablets containing Vitamin C, Vitamin E, Vitamin B2, calcium pantothenate, and L-cysteine. As a result of the formulation study, three coating layers, 2% under coating (UC), 38% build-up coating (BC), and 5% syrup coating (SC) were necessary for sufficient impact toughness, elegant appearance, and improvement of appearance stability after storage at 25 degrees C/75% RH for 6 months under open conditions. We… CONTINUE READING