Development and evaluation of investigational vena caval filters: the complementary roles of in vitro and in vivo studies.

@article{Proctor2003DevelopmentAE,
  title={Development and evaluation of investigational vena caval filters: the complementary roles of in vitro and in vivo studies.},
  author={Mary C. Proctor and Kyung Ja Cho and Lazar John Greenfield},
  journal={The Journal of surgical research},
  year={2003},
  volume={110 1},
  pages={241-54}
}
BACKGROUND The use of animals in medical research raises both ethical and economic concerns. Validated in vitro models allow extensive device testing prior to in vivo studies which limits the numbers of animals required to reach conclusions regarding efficacy and safety. MATERIALS AND METHODS In vitro studies were conducted in a vena caval simulator (ECU… CONTINUE READING

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