Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria

@inproceedings{Meya2009DevelopmentAE,
  title={Development and evaluation of a clinical algorithm to monitor patients on antiretrovirals in resource-limited settings using adherence, clinical and CD4 cell count criteria},
  author={David B. Meya and L. A. Spacek and Hilda Tibenderana and Laurence John and Irene Namugga and Stephen Magero and Robin L. Dewar and Thomas C Quinn and Robert Colebunders and Andrew Ddungu Kambugu and Steven J. Reynolds},
  booktitle={Journal of the International AIDS Society},
  year={2009}
}
BACKGROUND Routine viral load monitoring of patients on antiretroviral therapy (ART) is not affordable in most resource-limited settings. METHODS A cross-sectional study of 496 Ugandans established on ART was performed at the Infectious Diseases Institute, Kampala, Uganda. Adherence, clinical and laboratory parameters were assessed for their relationship with viral failure by multivariate logistic regression. A clinical algorithm using targeted viral load testing was constructed to identify… CONTINUE READING