Development and degeneration of retina in rds mutant mice: ultraimmunohistochemical localization of opsin.

@article{Jansen1987DevelopmentAD,
  title={Development and degeneration of retina in rds mutant mice: ultraimmunohistochemical localization of opsin.},
  author={Hans G. P. Jansen and Somes Sanyal and Willem J. de Grip and John J. Schalken},
  journal={Experimental eye research},
  year={1987},
  volume={44 3},
  pages={347-61}
}
In normal retina the developing photoreceptor cells first show presence of opsin over the distal ends of the ciliary protrusions. In a fully differentiated cell intense activity is seen over the rod outer-segment discs; some activity is also seen over the Golgi zone and near the distal ends of the inner segments but the other parts of the receptor cell appear negative. In the pigment epithelium opsin is seen only over phagosomes containing rod outer segment debris. In the homozygous rds mutant… CONTINUE READING

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