Development and characterization of xenograft model systems for adenoid cystic carcinoma

@inproceedings{Moskaluk2011DevelopmentAC,
  title={Development and characterization of xenograft model systems for adenoid cystic carcinoma},
  author={Christopher A. Moskaluk and Alexander S. Baras and Stefani Mancuso and Hao Fan and Robert G Davidson and Dawn C Dirks and Wendy L Golden and Henry F. Frierson},
  booktitle={Laboratory Investigation},
  year={2011}
}
Adenoid cystic carcinoma (ACC) is one of the most common malignancies to arise in human salivary glands, and it also arises in the glandular tissue of other organ systems. To address the paucity of experimental model systems for this tumor type, we have undertaken a program of transplanting tissue samples of human ACC into immunodeficient nu/nu mice to create xenograft model systems. In 17 of 23 attempts (74%), xenograft tumors were successfully grown. In all cases, the histologic appearance of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Similar Papers

Loading similar papers…