Development and characterization of solid lipid nanoparticles loaded with magnetite.

@article{Igartua2002DevelopmentAC,
  title={Development and characterization of solid lipid nanoparticles loaded with magnetite.},
  author={Manoli Igartua and Patrick Saulnier and B{\'e}atrice Heurtault and Brigitte Pech and Jacques Emile Proust and J. L. Pedr{\'a}z and Jean Pierre Benoit},
  journal={International journal of pharmaceutics},
  year={2002},
  volume={233 1-2},
  pages={
          149-57
        }
}
This paper describes the preparation of colloidal lipid particles containing magnetite from warm emulsions. A two step method was used to obtain the nanoparticles: (i) formulation of a transparent phase by heating a O/W emulsion (aqueous surfactant solution melted with a lipid phase, containing the ethyl oleate and soybean lecithin) in which modified lipophilic magnetite is incorporated, and (ii) preparation of the nanoparticles by dispersing the warm transparent phase in cold water (7 degrees… CONTINUE READING

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