Development and characterization of a PHB-HV-based 3D scaffold for a tissue engineering and cell-therapy combinatorial approach for spinal cord injury regeneration.

@article{RibeiroSamy2013DevelopmentAC,
  title={Development and characterization of a PHB-HV-based 3D scaffold for a tissue engineering and cell-therapy combinatorial approach for spinal cord injury regeneration.},
  author={Silvina Ribeiro-Samy and Nuno Sotero Alves da Silva and V{\'i}tor Manuel Correlo and Joana S Fraga and Lu{\'i}sa Pinto and Andreia Teixeira-Castro and H. Leite-Almeida and Armando J Almeida and Jeffrey M. Gimble and Nuno Sousa and Antonio Jose Gama Salgado and Rui Lu{\'i}s Reis},
  journal={Macromolecular bioscience},
  year={2013},
  volume={13 11},
  pages={1576-92}
}
Spinal cord injury (SCI) leads to devastating neurological deficits. Several tissue engineering (TE)-based approaches have been investigated for repairing this condition. Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHB-HV) is found to be particularly attractive for TE applications due to its properties, such as biodegradability, biocompatibility, thermoplasticity and piezoelectricity. Hence, this report addresses the development and characterization of PHB-HV-based 3D scaffolds, produced by… CONTINUE READING
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