Development and characterisation of a novel animal model of prostate inflammation-induced chronic pelvic pain

@article{Radhakrishnan2008DevelopmentAC,
  title={Development and characterisation of a novel animal model of prostate inflammation-induced chronic pelvic pain},
  author={Rajan Radhakrishnan and R. S. Nallu},
  journal={Inflammopharmacology},
  year={2008},
  volume={17},
  pages={23-28}
}
Chronic pelvic pain due to prostate inflammation is a significant clinical problem. In the current study we developed and validated an animal model of inflammation-induced pelvic pain (NIH category IIIA). 3 % carrageenan was injected into the ventral prostate in SD rats. At different time points (before and after 48 h, 72 h and 1 wk of injection), radiant heat and von Frey filaments (mechanical stimuli) were applied to different pelvic areas. The escape latency (s) from radiant heat, and the… CONTINUE READING

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