Development and applications of single-cell transcriptome analysis

  title={Development and applications of single-cell transcriptome analysis},
  author={Fuchou Tang and Kai Qin Lao and M. Azim Surani},
  journal={Nature Methods},
Dissecting the relationship between genotype and phenotype is one of the central goals in developmental biology and medicine. Transcriptome analysis is a powerful strategy to connect genotype to phenotype of a cell. Here we review the history, progress, potential applications and future developments of single-cell transcriptome analysis. In combination with live cell imaging and lineage tracing, it will be possible to decipher the full gene expression network underlying physiological functions… CONTINUE READING