Development and application of peptide-based radiopharmaceuticals.

@article{Dijkgraaf2007DevelopmentAA,
  title={Development and application of peptide-based radiopharmaceuticals.},
  author={Ingrid Dijkgraaf and Otto C Boerman and Wim J. G. Oyen and Frans H. M. Corstens and Martin Gotthardt},
  journal={Anti-cancer agents in medicinal chemistry},
  year={2007},
  volume={7 5},
  pages={543-51}
}
During the past decade, radiolabeled receptor-binding peptides have emerged as an important class of radiopharmaceuticals for tumor diagnosis and therapy. The specific receptor binding property of the ligand can be exploited by labeling the ligand with a radionuclide and using the radiolabeled ligand as a vehicle to guide the radioactivity to the tissues expressing a particular receptor. The concept of using radiolabeled receptor binding peptides to target receptor-expressing tissues in vivo… CONTINUE READING

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