Development and Validation of a Screening Assay for the Evaluation of Putative Neuroprotective Agents in the Treatment of Parkinson’s Disease

@article{YongKee2010DevelopmentAV,
  title={Development and Validation of a Screening Assay for the Evaluation of Putative Neuroprotective Agents in the Treatment of Parkinson’s Disease},
  author={Christopher J Yong-Kee and Danielle Salomonczyk and Joanne E. Nash},
  journal={Neurotoxicity Research},
  year={2010},
  volume={19},
  pages={519-526}
}
Following initial diagnosis of Parkinson’s disease, if it were possible to prescribe a treatment that could halt or prevent further neurodegeneration, disease progression could be prevented. The aim of this study was to generate a quick and reliable assay for assessing putative neuroprotective agents for parkinsonian patients. Abnormalities in mitochondria, proteasome and lysosome function, as well as oxidative stress cause cell death in Parkinson’s disease. Thus, we exposed neuroblastoma (SH… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 46 references

Levodopa/dopamine replacement strategies in Parkinson's disease--future directions.

Movement disorders : official journal of the Movement Disorder Society • 2008

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