Development and Validation of a Rp-hplc Method for Simultaneous Estimation of Lamivudine , Tenofovir Disoproxil Fumarate and Efavirenz in a Combined Tablet Dosage Form

Abstract

Objective: Development of an accurate, simple, precise and rapid method for estimating Tenofovir disoproxil fumarate, Lamivudine and Efavirenz simultaneously, in a combined tablet form. Methods: The method uses Reverse Phase High Performance Liquid Chromatography (RP-HPLC). Symmetry C18 (4.6 x 100 mm, 3.5 μm) column operated with a mixture of phosphate… (More)

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