Development and Validation of a Stability-indicating Hplc Method for Analysis of Celecoxib ( Cxb ) in Bulk Drug and Microemulsion Formulations

A simple, economic, selective, precise, and stability-indicating HPLC method has been developed and validated for analysis of celecoxib (CXB), a selective COX-2 inhibitor, both in bulk drug and in microemulsions. Reversed-phase chromatography was performed on a C18 column with methanol–water, 75:25 (%, v/v), as mobile phase at a flow rate of 1.25 mL min… CONTINUE READING