Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis.

@article{Hilbert2016DevelopmentAV,
  title={Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis.},
  author={David W. Hilbert and William L. Smith and Sean G. Chadwick and Geoffrey Toner and Eli Mordechai and Martin E. Adelson and Tina Jessica Aguin and Jack D. Sobel and Scott E. Gygax},
  journal={Journal of clinical microbiology},
  year={2016},
  volume={54 4},
  pages={1017-24}
}
Bacterial vaginosis (BV) is the most common gynecological infection in the United States. Diagnosis based on Amsel's criteria can be challenging and can be aided by laboratory-based testing. A standard method for diagnosis in research studies is enumeration of bacterial morphotypes of a Gram-stained vaginal smear (i.e., Nugent scoring). However, this technique is subjective, requires specialized training, and is not widely available. Therefore, a highly accurate molecular assay for the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Gardnerella vaginalis population dynamics in bacterial vaginosis

European Journal of Clinical Microbiology & Infectious Diseases • 2017
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Nonspecific vaginitis. Diagnostic criteria and microbial and epidemiologic associations.

The American journal of medicine • 1983
View 4 Excerpts
Highly Influenced

Anaerobic bacteria in nonspecific vaginitis.

The New England journal of medicine • 1980
View 5 Excerpts
Highly Influenced

Sexually transmitted diseases treatment guidelines, 2015.

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports • 2015

Similar Papers

Loading similar papers…