Development and Validation of a High-Performance Thin-Layer Chromatographic-Densitometric Method for the Quantification of Swertiamarin in Traditional Bitters and Formulations

@inproceedings{Ahamad2015DevelopmentAV,
  title={Development and Validation of a High-Performance Thin-Layer Chromatographic-Densitometric Method for the Quantification of Swertiamarin in Traditional Bitters and Formulations},
  author={Javed Ahamad and Naila Hassan and Saima Amin and Showkat Rasool Mir},
  year={2015}
}
Summary Plant bitters, traditionally used against loss of appetite and fever, owe their therapeutic efficacy to the content of iridoids such as swertiamarin. The aim of the study was to develop a simple, precise, rapid, and reliable high-performance thin-layer chromatography (HPTLC) method for the estimation of swertiamarin in traditional bitters and formulations. Aluminum-backed silica gel 60 F 254 plates (20 × 10 cm) were used as stationary phase and ethyl acetate– methanol–water (80:15:5, v… CONTINUE READING