Development and Validation of UV-Visible Spectrophotometric Baseline ManipulationMethod for Simultaneous Quantitation of Tenofovir Disoproxil Fumarate and Emtricitabine in Pharmaceutical Dosage Form

@inproceedings{Choudhari2015DevelopmentAV,
  title={Development and Validation of UV-Visible Spectrophotometric Baseline ManipulationMethod for Simultaneous Quantitation of Tenofovir Disoproxil Fumarate and Emtricitabine in Pharmaceutical Dosage Form},
  author={Vishnu P. Choudhari and Sanket R. Parekar and Subhash G. Chate and Pradeep D. Bharande and R. Raja Singh and Bhanudas S. Kuchekar},
  year={2015}
}
A simple, economical, precise, and accurate new UV-visible spectrophotometric baseline manipulation method for simultaneous determination of tenofovir disoproxil fumarate (TE) and emtricitabine (EM) in combined tablet dosage form has been developed. e method is based on baseline manipulation (difference) spectroscopy where amplitudes at 261 and 289.9 nm were selected to determine TE and EM, respectively, in combined formulation, and distilled water was used as solvent. Both drugs obey Beer’s… CONTINUE READING

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