• Corpus ID: 55419328

Development and Evaluation of Transdermal Patches of Quetiapine fumerate for the treatment of psychosis

@article{Garud2013DevelopmentAE,
  title={Development and Evaluation of Transdermal Patches of Quetiapine fumerate for the treatment of psychosis},
  author={Akanksha Garud and Navneet Garud and Akanksha Namdeo},
  journal={International Journal of Drug Delivery},
  year={2013},
  volume={4},
  pages={470-476}
}
The aim of the present study was to formulate and evaluate the transdermal patches of an antipsychotic drug Quetiapine fumerate (QF) for the treatment of psychosis and schizophrenia. The transdermal patches was prepared by the solvent evaporation method using hydroxy propyl methyl cellulose (HPMC) and ethyl cellulose (EC) in five different ratios 1:0, 2:1, 1:1, 1:2, 0:1. The PEG-400 and DMSO were used as plasticizers and permeation enhancer respectively to enhance the permeability of the drug… 
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