Development and Evaluation of Rutin-HPβCD Inclusion Complex Based Mouth Dissolving Tablets

@inproceedings{Bhalkar2018DevelopmentAE,
  title={Development and Evaluation of Rutin-HP$\beta$CD Inclusion Complex Based Mouth Dissolving Tablets},
  author={Hitendra S Mahajan and Krishna G Bhalkar},
  year={2018}
}
The objective of the present study was to explore inclusion complex of Rutin to improve the aqueous solubility and dissolution rate along with rapid mouth dissolving tablets for oral drug delivery. 
4 Citations

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Physico-Chemical and Pharmaco-Technical Characterization of Inclusion Complexes Formed by Rutoside with β-Cyclodextrin and Hydroxypropyl-β-Cyclodextrin Used to Develop Solid Dosage Forms

The aim of our study was to obtain rutoside (RUT) inclusion complexes in β-cyclodextrin (β-CD) and in hydroxypropyl-β-cyclodextrin (HP-β-CD), in a 1:1 molar ratio, using the lyophilization method of

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Information is presented concerning well researched phytoconstituents established as potential hypoglycemic agents for the prevention and treatment of diabetes and its associated disorders having restricted solubility and bioavailability related issues.

Development and Evaluation of Rutin-HPβCD Inclusion Complex Based Mouth Dissolving Tablets

The objective of the present study was to explore inclusion complex of Rutin to improve the aqueous solubility and dissolution rate along with rapid mouth dissolving tablets for oral drug delivery.

References

SHOWING 1-10 OF 25 REFERENCES

Preformulation Study of the Inclusion Complex Irbesartan-β-Cyclodextrin

The study indicated the usefulness of cyclodextrin technology to overcome the solubility problem of IRB and coevaporation was the best in which thesolubility was increased and dissolution rate of the drug was the highest.

Improvement of Dissolution Characteristics of Meloxicam by Complexation with Cyclodextrins

The aim of the present study was an attempt to prepare tablets containing inclusion complexes of meloxicam with β-cyclodextrins and hydroxypropyl-β-cyclodextrin to improve the aqueous solubility of

Characterization of an inclusion complex of cholesterol and hydroxypropyl-beta-cyclodextrin.

  • R. O. WilliamsV. MahagunaM. Sriwongjanya
  • Chemistry, Medicine
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 1998

Characterization of Cyclodextrin Inclusion Complexes - A Review

A critical review of the literature was carried out to characterize the formation of inclusion complexes by different techniques in the solid and in the solution state to determine the interaction of drug molecules with cyclodextrins which confirm the formationof inclusion complexes.

In vitro antioxidant properties of rutin

Synthesis and Characterization of the Inclusion Complex of β-cyclodextrin and Azomethine

The product was characterized by Fourier Transform Infrared spectrometer, 1H Nuclear Magnetic Resonance and Thermogravimetric Analyzer, which proves the formation of the inclusion complex where the benzyl part of azomethine has been encapsulated by the hydrophobic cavity of β-Cyd.

Essentials of Pharmaceutical Preformulation

Essentials of Pharmaceutical Preformulation is a study guide which describes the basic principles of pharmaceutical physicochemical characterisation and discusses their wider implication for pharmaceutical development, with reference to many case examples of current drugs and drug products.