Development and Characterization of Zaleplon Solid Dispersion Systems: A Technical Note

Abstract

Zaleplon (Fig. 1) is a pyrrazolopyrimidine hypnotic drug indicated for the short term (2 to 4 weeks) management of insomnia (1). It interacts with GABAA receptor and also shows some pharmacological properties of benzodiazepines (2). It also possesses potent anticonvulsant activity against pentylenetetrazoleand electroshock-induced convulsions (3) and is… (More)
DOI: 10.1208/s12249-008-9077-1

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