Development: Transcriptional activation at the maternal-to-zygotic transition

@article{Stower2011DevelopmentTA,
  title={Development: Transcriptional activation at the maternal-to-zygotic transition},
  author={Hannah Stower},
  journal={Nature Reviews Genetics},
  year={2011},
  volume={12},
  pages={805-805}
}
The authors investigated control of transcriptional activation during the maternal-to-zygotic transition (MZT) in Drosophila melanogaster by performing chromatin immunoprecipitation followed by sequencing (ChIP–seq) for the transcription factor Zelda. They found pervasive binding of Zelda at genomic regions that are activated in the MZT, and they found that… CONTINUE READING