Development: Extending the role of FGFs in the limb


the apical ectodermal ridge (AER) is essential for the development of the tetrapod limb along its proximal– distal (P–D) axis. Fifteen years ago it was shown that members of the fibroblast growth factor (FGF) family are the vital signals produced by the AER. But what do these FGFs do? A series of genetic studies shows that, contrary to the long-standing… (More)
DOI: 10.1038/nrg2385


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