Development: DNA methylation in Drosophila melanogaster

@article{Lyko2000DevelopmentDM,
  title={Development: DNA methylation in Drosophila melanogaster},
  author={Frank Lyko and Bernard H. Ramsahoye and Rudolf Jaenisch},
  journal={Nature},
  year={2000},
  volume={408},
  pages={538-540}
}
Certain cytosine residues of eukaryotic DNA are methylated in inactive regions of the genome. For a long time the fruitfly Drosophila was thought to be an exception, but now the evidence points to the existence of a functional DNA-methylation system in Drosophila as well. Here we show that DNA is methylated, but that Drosophila genomic methylation is restricted to the early stages of embryonic development. 
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