Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study.

@article{Turner2007DevelopmentVA,
  title={Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study.},
  author={Dan Turner and Anthony R Otley and David Mack and Jeffrey Hyams and Joep de Bruijne and Krista Uusoue and Thomas D Walters and Mary Zachos and Peter Mamula and Dorcas E. Beaton and A. Hillary Steinhart and Anne Marie Griffiths},
  journal={Gastroenterology},
  year={2007},
  volume={133 2},
  pages={423-32}
}
BACKGROUND AND AIMS Colonoscopic appearance, the primary measure of disease activity in adult ulcerative colitis, is less acceptable to children. Our aim was to develop a noninvasive activity index of pediatric ulcerative colitis. METHODS Item selection was performed judgmentally using a Delphi group of 36 experts in pediatric inflammatory bowel disease. Item weighting was performed by regression modeling using a prospective cohort of 157 pediatric ulcerative colitis patients. Validation was… CONTINUE READING
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