Development, optimization and characterization of nanoemulsion loaded with clove oil-naftifine antifungal for the management of tinea.

@article{Alghaith2021DevelopmentOA,
  title={Development, optimization and characterization of nanoemulsion loaded with clove oil-naftifine antifungal for the management of tinea.},
  author={Adel F Alghaith and S. Alshehri and Nabil A. Alhakamy and K. Hosny},
  journal={Drug delivery},
  year={2021},
  volume={28 1},
  pages={
          343-356
        }
}
Tinea is a common superficial infection caused by keratinophylic fungi called dermatophytes. The objective of the current investigation was to develop and optimize a self-nanoemulsion drug delivery system (SENDDs) using clove oil loaded with naftifine (NF). Clove oil possesses good anti-inflammatory and antifungal properties that can support naftifine action. Box-Behnken designs were used to prepare plain and naftifine loaded SENDDs. The plain SENDDs were evaluated for their globule size. The… Expand
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